Co-Tabuvan 80/12.5mg - 30 Tablet

                                    Product Description:

Please note that your doctor may have prescribed this medicine for different uses and/or at a different dose than indicated in the package leaflet.

Always follow your doctor's instructions as shown on the pharmacy label.

Valsartan/Hydrochlorothiazide coated tablets contain two active ingredients called valsartan and hydrochlorothiazide.

These two active ingredients help treat high blood pressure (hypertension).

Valsartan:

It belongs to a group of medicines called "angiotensin II receptor antagonists," which are used to treat high blood pressure.

Angiotensin II is a substance in the body that causes blood vessels to constrict, leading to increased blood pressure.

Valsartan works by blocking the effects of angiotensin II.

The result is that blood vessels relax and blood pressure decreases.

Hydrochlorothiazide:

It belongs to a group of medicines called thiazide diuretics (also known as "water pills").

Hydrochlorothiazide increases the amount of urine produced, which also lowers blood pressure.

Valsartan/hydrochlorothiazide is used to treat high blood pressure when treatment with either active ingredient alone is insufficient.

High blood pressure increases the workload on the heart and arteries. If left untreated, it can damage blood vessels in the brain, heart, and kidneys, and can lead to stroke, heart failure, or kidney failure.

High blood pressure increases the risk of a heart attack.

When blood pressure is lowered to normal levels, the risk of these problems is reduced.

Directions for Use:

Always use this medicine exactly as your doctor has told you.

This will help you achieve the best possible outcome and reduce the risk of side effects.

Contact a doctor or pharmacist if you are not sure.

People with high blood pressure often don't notice symptoms.

Many people feel well. Therefore, it's very important to keep appointments with your doctor, even if you feel well.

Your doctor will tell you exactly how many valsartan/hydrochlorothiazide tablets to take. Depending on how you respond to treatment, your doctor may suggest a higher or lower dose.

The recommended dose of valsartan/hydrochlorothiazide is one tablet daily.

Do not change your dose or stop treatment without consulting your doctor.

The medication should be taken at the same time each day, usually in the morning.

You can take valsartan/hydrochlorothiazide without regard to meals.

Swallow the tablet with a glass of water.

If you take too much valsartan/hydrochlorothiazide:

Contact a doctor or hospital if you take too much of the medication, or if a child accidentally takes the medication.

For other questions about the medication, contact your doctor or pharmacist.

If you feel very dizzy and/or feel like you're going to faint, you should lie down and contact your doctor immediately. Contact a doctor, pharmacy, or hospital if you accidentally take too many tablets.

If you forget to take Valsartan/Hydrochlorothiazide:

If you forget to take a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose. You should not take a double dose to make up for a missed dose.

If you stop taking Valsartan/Hydrochlorothiazide:

If you stop taking Valsartan/Hydrochlorothiazide, it may cause your blood pressure to worsen.

Do not stop using this medicine unless your doctor tells you to.

Ask your doctor or pharmacist if you have any questions about the use of this medicine.

Warnings and Precautions:

Do not use valsartan/hydrochlorothiazide:

If you are allergic (hypersensitive) to valsartan, hydrochlorothiazide, sulfonamide derivatives (compounds chemically related to hydrochlorothiazide), or any of the other ingredients of this medicine.

If you are more than 3 months pregnant (Valsartan/Hydrochlorothiazide should also be avoided during early pregnancy - see Pregnancy and Breastfeeding section)

If you have severe liver disease, where damage to the small bile ducts in the liver (biliary cirrhosis) leads to a buildup of bile in the liver (cholestasis)

If you have severe kidney disease

If you are not producing urine (anuria)

If you are undergoing dialysis treatment

If you have very low levels of potassium or sodium in your blood, or if you have too much calcium in your blood, despite treatment for these conditions

If you have gout

If you have diabetes or reduced kidney function and are being treated with a high blood pressure medicine containing aliskiren

If any of the above applies to you, contact your doctor and do not take Valsartan/Hydrochlorothiazide.

Talk to your doctor:

If you are using potassium-sparing medications, potassium supplements, salt substitutes containing potassium, or other medications that increase blood potassium levels, such as heparin. Regular monitoring of your blood potassium level may be necessary.

If you have low blood potassium levels.

If you experience:

Severe diarrhea or vomiting.

If you are using high doses of diuretics ("water pills").

If you have a serious heart condition.

If you have heart failure or have had a heart attack.

Follow your doctor's recommendations regarding your starting dose carefully.

Your doctor may also want to check your kidney function:

If you have renal artery stenosis.

If you have recently had a kidney transplant.

If you have hyperaldosteronism.

This is a condition in which the adrenal glands produce too much of the hormone aldosterone.

If this applies to you, you are not recommended to use valsartan/hydrochlorothiazide.

If you have liver or kidney disease.

If you have ever experienced swelling of the tongue and face caused by an allergic reaction called angioedema when using other medicines (including ACE inhibitors):

Inform your doctor. If you experience these symptoms while using valsartan/hydrochlorothiazide,

Stop using valsartan/hydrochlorothiazide immediately and do not use it again.

If you experience fever, rash, and joint pain, which may be symptoms of systemic lupus erythematosus (SLE, a so-called autoimmune disease).

If you have diabetes, gout, or high levels of cholesterol or fats (triglycerides) in your blood.

If you have previously experienced an allergic reaction when using other blood pressure-lowering medicines in the same group (angiotensin II antagonists), or if you have allergies or asthma.

If you experience blurred vision or eye pain.

These may be symptoms of increased pressure in the eye and may occur within hours or a week after starting valsartan/hydrochlorothiazide.

This can lead to permanent vision loss if left untreated.

You may be at greater risk of developing this if you have previously had allergic reactions to sulfonamides or penicillins.

Valsartan/hydrochlorothiazide may increase your skin's sensitivity to sunlight.

If you are using any of the following medications for high blood pressure:

ACE inhibitors (such as enalapril, lisinopril, ramipril), especially if you have diabetic kidney disease.

Aliskiren

Ingredients:

The active ingredients are a combination of two medications:

Valsartan/hydrochlorothiazide.

It is available in different strengths from several manufacturers:

Valsartan 80 mg / Hydrochlorothiazide 12.5 mg.

Valsartan 160 mg / Hydrochlorothiazide 25 mg.

Valsartan 160 mg / Hydrochlorothiazide 12.5 mg.

Valsartan 320 mg / Hydrochlorothiazide 12.5 mg.

Valsartan 320 mg / Hydrochlorothiazide 25 mg.

Product Details:

Brand: Co-Tapovan
Quantity: 30 Tablets
Product Form: Tablets
Product Type: Tablets